PYC3702 Ch 8 Substance-use Disorders

Substance Use - PAHO/WHO | Pan American Health Organization

Substance-use Disorder

Substance-induced disorders

Substance-Related Disorders

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DSM-5 Criteria for a substance-use disorder

At least 2 of the following over 12 months causing significant impairment/distress:

  • Using more or for longer than intended
  • Unsuccessful attempts to control substance due to cravings
  • Spending a lot of time getting, using or recovering from using
  • Craving/strong desires to use
  • Dropping out of responsibilities because of substance-use
  • social and interpersonal harm
  • impaired work, social and leisure activities
  • physical endangerment due to substance use
  • Continued use even though physical and psychological harm is occurring
  • Tolerance causing increased need for the substance
  • Withdrawal symptoms when the person tries to stop using, which trigger the person to start using again
Late stage alcoholism. Different people have different metabolic reaction to alcohol. Some people have instant addiction problem with their first drink. Others after a life-time of ‘normal’ social drinking.

What to remember

The essence is :

  • impairment & distress,
  • compelled by the substance/behavior
  • keeps getting worse

Gambling addiction

The gaming industry tries to feed into the gambling industry as gamers will know – for gaming, sex, or eating addictions, you can use the same rules of thumb.

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Minimum criteria for a diagnosis

4 of the symptoms for a year.

  • Tolerance causing increased need to gamble more money
  • Withdrawal symptoms of irritability & restlessness when the person tries to stop gambling
  • Gambling more or for longer than intended
  • Unsuccessful attempts to control gambling
  • Spending a lot of time gambling, thinking about gambling, finding money for gambling etc
  • Self-soothes with gambling when upset or distressed
  • Can’t stop coming back, tries to win back losses
  • Deceives others about the financial losses, extent of behavior etc
  • Has lost jobs, relationships etc
  • Has to get financial help because of gambling
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Severity of gambling addiction

  • mild: 4-5 symptoms
  • moderate: 6-7
  • severe 8-9

Substances that people abuse

Different substances have very different risk profiles and effects. Some people cannot touch any mind-altering substances at all -they are at high risk of developing a substance-dependency.

Some substances are dangerous to anyone who uses them. Heroin, for example, carries the risk of overdose or dependency once it is used past a particular fine line of quantity and number of doses, for any person at all.

Crack (crystalized cocaine) is instantly addictive for some people.

Human societies have been using mind-altering substances, such as alcohol, for thousands of years. Most people come through unscathed, but never all.

  • Depressants:
    • Alcohol
    • opioids – heroin, opium, fentanyl, oxycontin etc
    • sedatives, hypnotics, anxiolytics
  • Stimulants
    • caffeine
    • amphetamines – eg tik – crystal meth
    • cocaine
    • crack (cocaine crystals)
  • Hallucinogens
    • LCD
    • psilocybin
    • mescaline
    • salvia
  • Dissociative anaesthetics
    • Phencyclidine (PCP)
    • Ketamine, methoxetamine (MXE)
    • Dextromethmorphan
  • Substances with multiple effects
    • nicotine
    • cannabis
    • inhalants
    • Ecstacy (MDMA)
    • Gamma hydroxybutyrate (GHB)
For really horrific images and news stories, try googling Flakka – bath salts or the zombie drug.

Etiology of substance-Use Disorders

The progression from substance-use to addiction is not always typical, but the typical progression goes something like this:

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  1. Initial use: The decision to experiment
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2. Increasing use: Using the substance for a purpose – to numb painful emotions, to feel more confident or less anxious, to have fun, etc

Tik-tock: Hangberg's meth timebomb - The Mail & Guardian

3. Heavy Use: The brain chemistry begins to be altered, often causing physiological dependence, cravings, and withdrawal.

4. Drug Lifestyle: Lifestyle changes – life changes to follow the demands of the addiction, and as chronic use of the substance damages the person’s ability to function socially, professionally etc.

The 4 dimensions

Psychological Dimension

Social Dimension

Sociocultural dimension

Biological Dimension

monkey drug trials of 1969 by luis costa

Treatment

Substance-use disorder is entirely preventable, in theory anyway, by abstinence.

Recovery from active addiction is another matter entirely.

Narcotics Anonymous and Alcoholics Anonymous are long-standing peer-support organizations that help people recover from addiction.

Recovery Meeting Schedule - JC Recovery House

There are also many drug rehabilitation organizations that help people. However, they are often very expensive.

Rehab promo pic
In paradise, battling hell in a sober house | World | Breaking news and  perspectives from around the globe | DW | 16.02.2017
There are very affordable heart-centered rehabs available if you look hard enough.

To get clean, many people have to change their whole lives.

They need to find a sober social support network, end relationships with co-users, heal the emotional traumas and mental disorders that led them into addiction in the first place, and self-regulate intensely to avoid the exhaustion of will-power that leads to relapse.

Relapse Prevention: Strategies, Skills & Coping Techniques

Relapse is frequent, and usually leads back to usage of the substance. It is also very dangerous in the case of opioids, and frequently causes an overdose because the person can no longer tolerate the same dose as before.

Medications can help people through the withdrawal and early stages of abstinence.

Motivational enhancement therapy can help people in the process of making the decision of whether or not they want to get clean. The person needs to work through their ambivalence before starting the process, and this can help with this process, reducing the risk of relapse.

Drugs in South Africa – effects & risks

(Important for exams)

Parts of South African society are being destroyed by drugs, as we all know all too well. I am going to do my best to cut this down to what we may be examined on, not what we would like to understand better.

Humanizing the heroin epidemic: a photo essay

Heroin:

  • Ultimate painkiller, euphoric, then causing rebound depression.
  • Addictive after a few weeks of use.
  • Margin between feeling good and death by overdosing causing respiratory depression/ failure to keep breathing is very fine.
  • sharing needles increases risk of HIV &hepatitis
  • liver damage, seizures, coma, death
8 ways to sober up from being high | Leafly

Marijuana

  • relaxing mild hallucinogen
  • increased risk of psychotic disorders
  • long term damage of learning and memory
  • increased risk of heart attack and lung disease, including cancer
  • infertility
Wall Street Cocaine Stories

Cocaine

  • Stimulant – creates confidence and euphoria, rebound depression
  • addictive
  • sexually stimulating
  • heart & lung disease
  • brain damage
  • expensive
Homeless children sniff glue to take 'away the pain' of surviving Somalia's  streets

Solvents

  • glue, benzene, nail polish remover(acetone), spray paint
  • street children sniff off a piece of cloth
  • dizzy & drowsy
  • can’t concentrate, memory impairment, brain damage
  • weight loss
  • bone marrow damage

Mandrax (buttons)

  • Methaqualone
  • Central nervous system depressant
  • relaxation & euphoria, salivation followed by feeling weak, stomach pains, vomiting
  • cheap, but you need more and more
  • epilepsy, emotional problems, insomnia, toxic psychosis
What Happens to Your Brain and Body on Ecstasy

Ecstacy – MDMA

  • rave drug for all night dancing
  • mild euphoria, hallucinations, prosocial feelings, with rebound depression
  • rare risk of dehydration/overhydration and death
  • long term risks of brain damage, kidney failure, psychosis, convulsions
The Top 10 Worst Meth Transformations - Addiction Center

Tik -methamphetamine

  • stimulant giving feelings of confidence, power, sexuality
  • memory loss, weight loss, dental and skin problems, stroke
  • specifically high co-morbidity with anti-social personality disorder (not in exam)
South African townships' addictive drug cocktail - BBC News

Nyaope

  • South African street drug cocktail: unpredictable mix of heroin, dagga, mandrax, antiretroviral drugs, etc, so highly addictive and cheap
  • swallowed, smoked or injected
  • Extremely high risk of injury or death